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Document thoroughly Payers require documentation of history, examination, medical decisionmaking, time spent and procedures performed

Katagiri C, Masuda K, Urano T, Yamashita K, Araki Y, Kikuchi K, et al

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The most robust clinical evidence to date concerns the improvement of muscular and metabolic parameters (strength, endurance, insulin sensitivity) and the modulation of chronic inflammation. A 2024 randomised trial comparing NAD IV with NR IV in healthy adults showed that both modalities increase the available NAD pool, with a favourable safety profile

Another proof-of-concept trial, meticulously designed as a randomized, double-blind, placebo-controlled study, scrutinized the safety and effectiveness of Rhodiola capsules among 100 individuals grappling with mild to moderate major depressive disorder over a span of 12 weeks