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Methods: Using the UNOS database, a retrospective cohort was extracted of recipients of first liver transplant with renal dysfunction (estimated GFR 2 mg/dL) and the impact of pre-LT MELD, pre-LT renal disease (acute kidney injury [AKI] or chronic kidney disease [CKD]), liver disease etiology (MASH vs alcohol-related liver disease [ALD] and other non-MASH), and 1-year trough tacrolimus (Tac) level on developing renal dysfunction following LT

Qualitative variables were presented as frequencies and percentages, and quantitative variables as mean standard deviation (SD)

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Code availability All scripts used for simulations in this research are publicly available (GitHub diederiklt/YeastHighTemperatures)

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