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The antioxidant effect of NO is evident in its ability to react with the superoxide anion to form peroxynitrite (ONOO-), a reaction that reduces levels of ROS within the cell, thereby alleviating oxidative stress (96)

maximal [ 51 Cr] release was determined by adding Triton-X (2% final concentration) to target cells, and basal release measured in the absence of antibodies

Therefore, in-depth investigation into the mechanisms associated with cerebellar inflammation, particularly in relation to local metabolism and microglial function, is essential

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However, phenotypic changes often manifest several years earlier, driven by early pathogenic processes in a so-called prodromal phase (Berg et al., 2015)

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