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KDM3A or KDM4C suppression resulted in robust DNA damage response and aggravated cellular senescence, whereas KDM3A or KDM4C overexpression promoted heterochromatin reorganization and decreased DNA damage response [106]

ER Signaling increased IL-17A production in th17 cells by upregulating IL-23R expression, mitochondrial respiration, and proliferation

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Compared with a low-Se diet (0.05 mg/kg), a high-Se diet (1.5 mg/kg) maintained postischemic plasma GSH levels and GPX activity and improved myocardial infarct size and postischemic mean arterial blood pressure in rats [115]

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Investigation of analgesic and anti-pyretic activity of escin in Wistar rat and Swiss mice