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Even with infrequent attacks, hyperuricemia leads to crystal formation in joints over time

Injection site reactions including minor redness, swelling, or tenderness occur in some users but typically resolve within hours

A few exceptions to this rule include those who suffer from a rare hereditary eye complaint known as Lebers disease

Pharmacology Research & Perspectives 9(3):e00755

used in long-term human clinical trials Intravenous injection Used primarily for pharmacokinetic characterization and acute dosing studies in humans Intraperitoneal injection Standard route for chronic rodent studies