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Description

BPC-157 contributes cytoprotection and VEGFR2-mediated angiogenesis

Nature 515 , 355364 (2014)

In addition, the SOCS gene is activated by GH signaling and works as a short intracellular negative feedback loop which rapidly down-regulate GHR activity by internalization and receptor ubiquitinoylation resulting in lysosomal and proteasomal degradation (101)