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TRPM2-deficient microglia exhibited increased LC3A/B-II levels, indicative of autophagosome formation, and decreased SQSTM1/p62 levels, suggesting enhanced autophagic flux

10.1177/0960327113499167 Hum Exp Toxicol

2016;12(9):e1005821

Activated LINE elements generate abundant RNADNA hybrids, which are recognized as foreign nucleic acid signals by the cGAS-STING pathway, inducing immune responses and amplifying inflammatory signals closely linked to neuroinflammation in AD

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