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An intriguing aspect of biogenesis is its regulatory crosstalk with other epitranscriptomic marks

For linear regressions between two variables (for example air pollution and a specific mitochondrial measures) without a mediating variable, a power analysis assuming a medium effect size f 2 = 0.15 and N = 96 finds a power of 96% for = 0.05 and 89% for = 0.0125

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e.g., under nutrient starvation, being able to provide substrates for ATP production and macromolecule synthesis (Zhang, 2013)

Oncotarget 7 (42), 6769967715 (2016)

Iyengar A, Wu CF (2021) Fly seizure EEG: field potential activity in the Drosophila brain