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5 Role of ROS and mitochondrial damage in RA bone destruction and cartilage damage Articular damage is a serious complication of RA that can lead to irreversible joint deformity, severely limiting joint mobility and affecting the quality of life of patients (215, 216)

Chemotherapy drugs Glutathione's antioxidant activity could theoretically reduce the effectiveness of certain chemotherapy agents that rely on oxidative mechanisms

Age and the effect of exercise, nutrition and cognitive training on oxidative stress the vienna active aging study (VAAS), a randomized controlled trial