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Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

Reference: 2002 Blackwell Science Ltd, British Journal of Haematology 116: 7886 Reference Publications Li, Y., Xie, S., Chen, M., Li, H., Wang, Y., Fan, Y., An, K., Wu, Y., & Xiao, W

Given that the cellular thiol network, including GSH, involves crosstalk between the cytosol and organelles, we selected two of the dysregulated enzymes, which had been identified by 2D electrophoresis, with important roles in mitochondrial function, i.e., Aco2 and mitochondrial creatine kinase (mtCK) (Fig

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