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Am J Respir Crit Care Med (1994) 149(3 Pt 1):81824

Inflammatory stimulation upregulates DMT1 expression in neurons, astrocytes, and microglia, induces hepcidin production in astrocytes and microglia, and downregulates FPN1 expression in all 3 cell types, leading to increased iron accumulation in neurons and microglia (Urrutia et al., 2013)

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doi: 10.1128/mBio.00062-19 75 RowanFDochertyNGMurphyMMurphyBCoffeyJCOConnellPR

Dimethyl Fumarate (DMF, Tecifidera ) is an NRF2 activator in clinical use for the treatment of relapsing forms of MS and psoriasis

Chen found in human melanoma cells that silencing iPLA2 would enhance the sensitivity to p53-mediated ferroptosis without significant effects on cells that usually express iPLA2, suggesting that iPLA2 can inhibit p53-mediated ferroptosis, and p53-driven ferroptosis is independent of GPX4 [41]