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Each group was supplied with drinking water (DW) from a separate container

The group used immunohistochemistry to assess the effect of either histamine deficiency ( Hdc KO mouse model) or histamine stimulation in wild type mice on microglia

This phase relies heavily on the Cytochrome P450 (CYP450) superfamily of enzymes, which are heme-containing monooxygenases located primarily in the smooth endoplasmic reticulum of hepatocytes (liver cells)