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Conflicts of interest The authors have no conflicts of interest to declare

Results Histological results Hematoxylin and Eosin-stained sections from the sham group showed preserved tissue architecture with normal complete spermatogenesis (Fig

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Investigators LI-H: Long-term efficacy and safety of lerodalcibep in heterozygous familial hypercholesterolaemia: the LIBerate-HeFH trial

Preclinical and phase 1 assessment of antisense oligonucleotide bepirovirsen in hepatitis B virustransgenic mice and healthy human volunteers: support for clinical dose selection and evaluation of safety, tolerability, and pharmacokinetics of single and multiple doses