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95,96 8-oxoG can mispair with adenine and therefore leads to GT mutations during DNA replication

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Regulation of ferroptosis-related signaling pathways in cancer drug resistance GPX4 and FSP1 signaling As mentioned earlier, GPX4 is a GSH-dependent ferroptosis inhibitor that reduces lipid peroxides, whereas FSP1 functions independently of GSH, which acts as an oxidoreduction enzyme reducing coenzyme Q (CoQ) to ubiquinol (CoQH2) at the cell membrane