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While the benefits of single antioxidant therapy may be limited and may even have negative effects, for example, long-term use of beta-carotene may increase the incidence of lung cancer in smokers (60), while vitamin E may increase the risk of bleeding in people with oral anticoagulants and even reduce the lipid-lowering effect of statins (61), Therefore, the safety and efficacy of long-term additional oral antioxidants deserve further exploration

For chronic social anxiety, twice-daily dosing of 12-20 IU may provide sustained benefits

doi: 10.1016/j.neulet.2021.136342 122

Copper tripeptide-1 (GHK-Cu) is the most studied copper peptide, originally isolated from human plasma and proposed to promote dermal papilla cell activity and VEGF-driven scalp vascularity

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Med Toxicol Adverse Drug Exp 1988;3:430-48