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Evidence: Systematic review shows B12 significantly improves diabetic neuropathy symptoms vs placebo (Hasan et al., 2019)

Besides diet, there is currently great interest in the use of probiotics and prebiotics, such as Lactobacillus plantarum MB452 or Lactobacillus rhamnosus GG, which have been shown to improve intestinal epithelium survival and cell junction expression, while administration of Bifidobacterum infantis has been correlated with reduced serum endotoxins in mice [15]

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\n\n\n\n Preclinical studies show BPC-157 promotes tendon repair by stimulating fibroblast proliferation, upregulating VEGF-mediated angiogenesis, regulating matrix metalloproteinase activity, activating the nitric oxide pathway, and enhancing growth factor expression in injured connective tissue