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Yoshino, S., E

[30] Temperature excursions below 15 C or above 30 C hasten hydrolysis of the phosphate ester and may cause visible particulates, so household refrigerators and hot vehicles should be avoided

Bolze S, Bromet N, Gay-Feutry C, Massiere F, Boulieu R, Hulot T

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8 On top of all of that, it is a metal chelator and binds to iron, preventing all the havoc those ferrous free radicals may cause

The imbalance between bone resorption by osteoclasts and bone formation by osteoblasts is the major contributor to the development of bone damage in RA, and ferroptosis further exacerbates this process