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At this time: Long term safety data is not available Human dosage guidelines are not established Side effects are not fully documented Use remains research based It should not be used casually or without medical supervision

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In the cohort of ALS patients, however, we found evidence for an inverse association between high serum IGF-1 concentrations and overall survival

doi: 10.1038/srep39752

it works better when taken along with a good diet and regular physical activity

Also, a number of vitamins and minerals are absorbed in the first portion of the small intestine that is bypassed, requiring supplements for life