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The lack of vitamin B12 may result from any of the following conditions: Addisonian (pernicious) anemia this condition causes autoantibody formation against parietal cells, which results in a lack of IF essential for absorption of vitamin B12 from the intestine Malabsorption impaired absorption of vitamin B12 Gastrointestinal pathology, dysfunction, or surgery these include atrophic gastritis, celiac disease, small bowel bacterial overgrowth, pancreatic insufficiency, Helicobacter pylori infection, gastric carcinoma, and total or partial gastrectomy Diphyllobothrium latum and related species (the fish tapeworm) infestation these parasites compete with vitamin B12 for intestinal absorption

Interestingly, in various studies, no association between anti-oxidant vitamins and asthma could be found [6,7], most likely due to dissimilarities in the basic diets in different regions, the potential fortification of food or supplementation from different sources (herbal or natural medicines, OTC (over the counter), or prescribed drugs), and the possibility of non-controlled use of vitamin supplements

Apr 2010;2(4):170-173

Ligand conjugated targeted nanotherapeutics for treatment of neurological disorders

Carbon-based nanozymes: design, catalytic mechanism, and bioapplication

[6] 1 in 5,000 have some form of EDS worldwide