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As a result of these efforts, we have gained insights into the potential of senotherapeutics to induce the demise of senescent cells, thereby exerting anti-cancer effects

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Pharmacologically, administration of the NRF2 inducer tertiary butylhydroquinone during gestation restored insulin sensitivity and glucose tolerance and increased the number of surviving offspring in a pregnant leptin-deficient mouse model ( db/ +) of GDM (77)

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Patients with personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 should avoid both medications

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