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[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Hickok J.R., Sahni S., Shen H., Arvind A., Antoniou C., Fung L.W.M., Thomas D.D

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Interestingly, inhibiting DDAH reduces TGF-/Smad-mediated collagen synthesis in fibroblasts and limits alveolar type II (ATII) cell proliferation in an ADMA-dependent manner [81, 84]

A phase Ib study showed that R1507 is well tolerated when added to six standard chemotherapy regiments in patients with various solid tumors, including BrCa [128]

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