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This instability poses major challenges for its development as an API-grade (active pharmaceutical ingredient) drug, restricting its use mainly to complex garlic preparations rather than as a purified pharmaceutical (Zhou et al., 2025

it's the evidence-based threshold where degradation becomes statistically significant

10.15252/embj.201696151 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang Z.Z., Lee E.E., Sudderth J., Yue Y., Zia A., Glass D., Deberardinis R.J., and Wang R.C

He doesnt get it hardly at all now and when it does, it only comes in a small patch on his legs, whereas before he was screaming in pain from the rash

Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways