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Therefore, the abundance and location of intracellular oxidizable substrates also determine the degree of lipid peroxidation and ferroptosis (Han et al., 2020)

Rev Environ Contam Toxicol 173:137 Baumann PC, Harshbarger JC, Hartman KJ (1990) Relationship between liver tumors and age in brown bullhead populations from two Lake Erie tributaries

While metabolomics focuses on identifying and quantifying the metabolites, fluxomics has emerged as the process of studying metabolic fluxes, or the rates of biochemical reactions, in a biological system, which is a more dynamic and quantitative approach to understanding metabolism (Emwas et al., 2022)

And some of the labeling, especially the axes and legend, appears to be low resolution

Immunosuppressive agents with intrinsic antifungal activity are emerging as candidates for drug repurposing, including calcineurin inhibitors (e.g., cyclosporine, pimecrolimus, tacrolimus/FK506), mTOR inhibitors (e.g., rapamycin), antimetabolites (e.g., mizoribine [MZP], mycophenolic acid [MPA]), and glucocorticoids