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Acknowledgements This insight article was supported by the National Natural Science Foundation of China (81901107) and the China Postdoctoral Science Foundation (2018M632872)

JUN, VEGFA, IL1B, CD4, STAT3, MAPK3, MMP2, ICAM1, CDC42, MAPK8, MDM2, LCK, MCL1, and HDAC1 were identified as the core targets sorted by degree (Figure 11B), which also confirmed the multitargeting of FRP against AD

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