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Benefits and side effects Despite being designed for specific elimination of drug-resistant cancer cells, ferroptosis therapies can exhibit side effects of varying unpredictability and severity, dependent on tumor types and treatments

J.2003Oxidative damage to Catalase induced by peroxyl radicals: Functional protection by melatonin and other antioxidants

V, Kumar S, Mishra GP, Mishra D, Rai GK, Jha GK, Kumar SN, Praveen S, Tyagi A and C

doi: 10.1016/j.ejogrb.2018.02.024 161 BrunseADengLPanXHuiYCastro-MejiaJLKotWet al

Methylation at R248 inhibits MDH1 post-translational mechanisms by disrupting MDH1 dimerization, which modulates mitochondrial respiration and glutamine-dependent production of NADPH in pancreatic cancer cells