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The development of CIPN is likely multifactorial and involves effects on neuronal and/or mitochondrial DNA and gene expression, axonal transport, ion channel expression and function, as well as neuroimmune mechanisms

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L-Glutamine supplementation is mostly recommended to: Sickle cell disease patients Cancer patients who are under chemotherapy Critically ill patients with too low L-glutamine in the body after trauma or surgery Individuals who are experiencing leaky gut syndrome or inflammatory bowel disease Athletes or fitness enthusiasts who engage in high-impact exercises, prolonged intense training, which depletes L-glutamine stores

Biochimie 100, 7887.CrossRefGoogle ScholarPubMed Gutierrez-Mariscal, FM, Yubero-Serrano, EM, Villalba, JM, Lopez-Miranda, J (2019) Coenzyme Q(10): From bench to clinic in aging diseases, a translational review

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Wound Recovery Models Animal and cellular research indicates that GHK may contribute to wound closure, angiogenesis, and remodeling of connective tissue