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These peptides often have multiple mechanisms of action, making it more difficult for bacteria to develop resistance

In preclinical models, ERR activation: Stimulates expression of genes associated with aerobic exercise adaptation Enhances mitochondrial biogenesis and oxidative respiration Increases fatty acid oxidation in skeletal and cardiac muscle Supports endurance capacity and metabolic flexibility Because of these effects, the compound has been described in the literature as an exercise mimetic a molecule that may reproduce certain biochemical signatures of physical training without the training stimulus itself

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The biotin-labeled cRNA was then purified, fragmented and hybridized to the arrays in the GeneChip Hybridization Oven 645 (Affymetrix