My general approach: Insufficiency range (145 to 220 pmol/L), intact gastric anatomy: oral methylcobalamin 1000 mcg daily
The other advantage of this approach, as noted by the authors, in addition to simply applying the chlorhexidine, is that different areas of the body can be specifically targeted
Abbreviations RPL: Recurrent pregnancy loss ART: Assisted reproductive technology APS: Antiphospholipid syndrome ETC: Electronic transport chain ROS: Reactive oxygen species RNS: Reactive nitrogen species MnSOD: Manganese superoxide dismutase Cu/ZnSOD: Copper/zinc superoxide dismutase NADPH: Nicotinamine adenide dinucleotide phosphate CAT: Catalase GPx: Glutathione peroxidase GR: Glutathione reductase GOx: Glutathione oxidase UV: Ultra violet GSH: Glutathione GSSG: Oxidised glutathione MDA: Malondialdehyde H 2 O 2 : Hydrogen peroxide OH : Hydroxyl radicals ROO : Peroxyl radicals PC: Protein carbonyl 8-OHG: 8-Hydroxyguanosine 8-OHdG: 8-Hydroxydeoxyguanosine SOA: Superoxide anion TAC: Total antioxidant capacity TOL: Total oxidant level NO: Nitric acid LPO: Lipid peroxidation PUFA: Polyunsaturated fatty acids OS: Oxidative stress NS: Nitrosative stress aCL: Anticardiolipin antibodies Se: Selenium Zn: Zinc Cu: Cooper Mn: Manganese GST: Glutathione S-transferase NAC: N -Acetylcysteine FGF: Fibroblast growth factor VEGF: Vascular endothelial growth factor VEGFR: Vascular endothelial growth factor receptor N 2 O: Nitrous oxide NO3 : Peroxynitrite HNO 3 : Peroxynitrous acid NOS: Oxide synthase References ESHRE Guideline Group on RPL, Bender Atik R, Christiansen OB, Elson J, Kolte AM, Lewis S, Middeldorp S, et al
"GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration." BioMed research international 2015 (2015)
For one, mood disorders like depression can decrease your interest in pleasurable activities (yes sex, but pleasure in general), decrease your self esteem, and lower your energy in ways that put sex and orgasm very low on your list of priorities
J Chem Theory Comput 10:51615177
