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The gut-barrier connection here is central: intestinal permeability (leaky gut) and immune dysregulation arent separate problems

Direct reprogramming without entering pluripotent cell state shortens the time for cell differentiation and lower the risks of tumorigenesis, which is deemed as a promising method to yield hepatocytes for HTx

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More recent research published in Frontiers in Pharmacology (2021) demonstrated accelerated wound healing in animal models through increased blood flow and collagen repair