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Strongest human evidence (topical) The Leyden 2002 photoaging trial in 71 women applied a GHK-Cu facial cream for 12 weeks and reported measurable improvements in skin density, thickness, fine lines, and laxity

Most studies report that this phase starts about 6 to 8 weeks after injury

If the joint width exceeds 1/2, use a foam backer rod

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We typically start low, go slow, and pair folate with the right B12 form (often methylcobalamin, sometimes adenosyl- or hydroxocobalamin) while tracking symptoms and labs

It is not a drug, supplement, or medical product and is not approved for human or animal use, diagnosis, or treatment