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Nutritional information: 100 ml Per serving (10 ml) *RM L-Carnitine 20 mg 2000 mg ** Inulin 500 mg 50 mg ** Green tea (Camellia sinensis) leaf extract 50 mg 5 mg ** Thiamine 14 mg 1.4 mg 127% niacin 180 mg 18 mg 112.5% Pantothenic acid 65 mg 6.5 mg 108% Vitamin B6 40 mg 4 mg 286%

Neuropsychopharmacol 27 , 410420 (2002)

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Patients with PCOS may experience: reproductive abnormalities inflammation correlated with insulin resistance irregular or absent menstrual periods excess androgens (male hormones such as testosterone) polycystic ovaries resulting from the hormonal imbalances hirsutism (male-patterned hair growth) acne alopecia (thinning or loss of scalp hair) Additionally, both reproductive-age and older women with PCOS have an increased risk for conditions such as: impaired glucose tolerance type 2 diabetes mellitus elevated cholesterol or lipids increased abdominal adiposity obesity hypertension metabolic syndrome depression anxiety obstructive sleep apnea nonalcoholic fatty liver disease endometrial cancer cardiovascular disease Research suggests that medication alone might not be enough to address PCOS

Discussion In this study, we demonstrated that PQQ has the potential to protect against oxidative stress-induced premature cellular senescence in auditory cells by enabling the recovery of mitochondrial function by restoring the regulation of SIRT1/PGC-1, the protein expression of SIRT1, and the deacetylation of PGC-1, and by facilitating the recovery of mitochondrial biogenesis including the ATP production rate and maximum respiration rate