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These molecules feed directly into the mitochondrial electron transport chain, which generates adenosine triphosphate (ATP) the primary energy currency of the cell

However, some observational studies have reported no such correlation, and randomized controlled trials have shown no improvement in cognitive function among older adults with or without dementia, mild cognitive impairment, or Alzheimers disease when supplemented with vitamin B12 alone or in combination with folic acid, vitamin B6, or both

To the contrary, some research has identified a link between vitamin deficiencies and changes in a persons sleep quality

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Large amounts of B12 can potentially interact with some drugs used for diabetes, heartburn, seizures, and more

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