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The policy to perform liver biopsy in high-risk patients above the recommended threshold of 9.6 kPa if any clinical doubt exists regarding the diagnosis of cirrhosis leads to a histological down staging in almost 80%

Beaufay H, Jacques P, Baudhuin P, Sellinger OZ, Berthet J, De Duve C (1964) Tissue fractionation studies

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in general, most of ezrin in the CNS is localized to astrocytes 422