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Int J Mol Sci 20(1):50

10.1016/j.exppara.2012.12.007 71 GarciaE

& Pantel, K

Melatonin suppression leads to increased oxidative stress and DNA damage, mediated by pathways involving the p53 tumor suppressor and the NF-kB signaling cascade, which are implicated in cancer and metabolic disorders (Stevens and Zhu, 2015