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Amino acid powders offer flexibility in dosing and typically mix easily with water or other beverages, making them popular for consumption during workouts

One RCT reported that L-carnitine co-administered with magnesium hydroxide significantly reduced serum AST and ALT (64), while another study found combined L-carnitine and resistance training superior to either intervention alone for liver enzyme reduction (65)

Activation of the TRP-KYN pathway appears to play a significant role in most cancer types

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Olivier Niggli, WADAs Director General, said: We encourage athletes, their entourage and all stakeholders to acquaint themselves with the Summary of Major Modifications to avoid inadvertent use of substances and methods that are prohibited in sport for 2025. Athletes and their support personnel should make themselves aware of the changes, review any medications they use, and apply for a TUE, if required, before the updated list comes into effect on 1 January 2025