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Several drugs that target mGluRs are used to restore the excitation and inhibition balance in brain cortical regions

Neuron 97 , 742768 (2018)

This process is driven by the accumulation of ROS and the peroxidation of polyunsaturated fatty acids in cellular membranes, leading to the formation of lipid hydroperoxides that compromise membrane integrity and cause cell swelling and death

In short, BPC stands for Body Protection Compound and it is 15 amino acids long

1 Even in darkness, the retina consumes large amounts of oxygen-often more than it does in light-making it particularly vulnerable to oxidative damage

In this study, FKB targeted TLR2 to inhibit the formation of the TLR2-MyD88 complex, thereby suppressing the NF-B signaling pathway both in vivo and in vitro