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Amino acid metabolism in drug resistance With increased demand for nutrients during chemotherapy, cancer cells have been shown to upregulate L-type amino acid transporter 1 (also known as SLC7A5), which helps in the transportation of branched chain amino acids, such as leucine, isoleucine, valine, and bulky amino acids such as phenylalanine, tryptophan, tyrosine, methionine, glutamine, asparagine, and histidine, and is associated with TNBC [31, 122, 123]

GHK-Cu (Copper Peptide) GHK-Cu is a naturally occurring copper-binding peptide found in human plasma and wound fluid, known for its strong regenerative and anti-inflammatory properties

In conclusion, SAC exerts antioxidant and anti-ferroptotic effects by modulating the Keap1/Nrf2/GPX4 signaling axis

Zhang Y, Ma R, Deng Q, Wang W, Cao C, Yu C, et al

She ate few animal products and didnt supplement with vitamin B12, so she became B12-deficient and began experiencing weakness, tiredness, numbness, and tingling

In addition, breast cancer cells divert excess PUFAs into TAGs and store them in LDs, effectively buffering oxidative stress from an excess of lipids and sustaining cell viability under the pressure of hypoxia and ferroptosis 105,106