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The regulation of the expression of excitatory amino acid carrier 1 (EAAC1) is promoted by Nrf2

It modulates inflammatory signaling, which is part of why it's used alongside injuries

Wang P, Chen H, Qin H, et al

Additionally, when we compared young and aged WT or Mda5 -/- HSCs, we observed an opening of chromatin in the aged populations that was distributed similarly in different genomic regions (Fig