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Another study shows that JQ1 can inhibit BRD4 expression and ultimately induce ferroptosis through two pathways, either by inhibiting the histone methylase G9a or by activating the histone deacetylase SIRT1, which can recognize the acetylation site and recruit transcriptional factors (Sui et al., 2019)

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In another study, interleukin-6 levels were elevated in the fat from women with Dercum disease compared to women without lipedema supporting Dercum disease as an inflammatory disorder (226)