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Within the melanosome, the enzymatic reduction of the amino acid tyrosine to melanin is catalyzed by the enzyme tyrosinase

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Lotz C, Lin AJ, Black CM, Zhang J, Lau E, Deng N, Wang Y, Zong NC, Choi JH, Xu T, Liem DA, Korge P, Weiss JN, Hermjakob H, Yates JR 3rd, Apweiler R, Ping P

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As we age, we make less collagen, which leads to wrinkles