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Mitochondria-targeted antioxidants mitoQ and mitoTEMPO do not influence BRAF-driven Malignant melanoma and KRAS-driven lung cancer progression in mice

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c , 4 month-old WT mice were treated with a single injection of vehicle (Ctrl) or Ab68 (5 mg/kg)

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As an ectoenzyme, CD38 catalyzes conversion of NAD + to nicotinamide, which is then almost completely reused for NAD + synthesis via the salvage pathway (Fig