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Stephen Ridgeway explains the health dangers of sitting for too long in a car or airplane.

Johnson DK, Schillinger KJ, Kwait DM et al (2002) Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

Semaglutide produces approximately 14.9% average body weight loss over 68 weeks in trials

The two worth knowing: Magnesium threonate: crosses the blood-brain barrier, increases brain magnesium levels, linked to cognitive benefits and synaptic plasticity Magnesium bisglycinate: gentler on the stomach, better for relaxation and sleep quality, does not cross the brain as readily but the systemic relaxation still helps sleep Rhonda takes both depending on the goal

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Examples of circadian-regulated physiological pathways includes cell growth, DNA repair and damage, angiogenesis, apoptosis, metabolism, redox state, as well as immune and inflammatory processes 25,26,27,28