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387,388,389 Oxidation-reduction modifications also participate in the regulation of AMPK activation, where Cys130 and Cys174 of AMPK can form disulfide bonds through oxidation, thereby impeding the binding of AMPK kinase to AMPK and subsequent AMPK activation

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Gout Medscape Reference Colchicine: Lower doses for greater safety Medsafe Out with Gout PHARMAC information for patients with gout 2012 American College of Rheumatology Guidelines for Management of Gout