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Decreasing the release of glutamate from the glutathione cycle by blocking GGT leads to diminished mEPSC

With enhanced metabolism of HCC cells, competition for nutrients leads to increased FAO and decreased aerobic glycolysis, promoting ROS expression and inducing nuclear factor (Nrf2)-mediated M2 polarization (147, 148)

doi:10.3390/jpm12081194 Rolf C, Knie U, Lemmnitz G, Nieschlag E

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