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High homocysteine can cause oxidative stress, mitochondrial dysfunction, and endoplasmic reticulum stress

doi: 10.1016/j.jconrel.2020.05.031

doi:10.1039/c2cs35172b 81

There are many well established nanoparticle drug delivery systems and most of their surfaces can be chemically modified readily, or their materials can be manipulated

There was an observable increase in the number of variants which fell below this threshold upon increase in APR-246 concentration, in both SKOV3 and OVCAR5 (Fig