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Furthermore, they showed that the inhibition of DNA methylation using decitabine resulted in the upregulation of ADH1B and ADH1C , whereas the inhibition of histone deacetylases (HDACs) using trigonelline A promoted ADH1C expression

Several recent studies have provided direct evidence, such as two-photon in vivo imaging, to show the pedigree relationship between reprogrammed glial cells and newborn neurons ( in situ transdifferentiation technology is still in the exploratory stage, and more exploration is needed in the future to provide more treatments for neurodegenerative diseases

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J Biol Chem 285(22):1663216642

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Although zinc and copper are regarded as essential minerals in human body, toxic effects exist when the absorption of minerals is in excess (Cal et al., 2005)