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Here, we investigate the mechanisms contributing to brain overgrowth by generating human induced pluripotent stem cells (iPSCs) from deeply phenotyped and genotyped children whom we assessed longitudinally from age 2 to 12 or beyond through the UC Davis MIND Institute Autism Phenome Project (APP)

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Delton Family Distinguished Professor in Organic Chemistry, and Joshua Munger, professor in the Department of Biochemistry and Biophysics and an expert in cancer cell metabolismare exploring ways to refine potential drugs that could inhibit this process and improve outcomes for patients

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doi: 10.1016/j.jada.2009.05.011