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Another study reported the interplay between ROS and SIRT1 in cell death during EV71 infection, and inhibition of ROS by NAC was shown to reduce EV71 propagation 149

In this metabolic context, most of the glucose 6-phosphate is first converted into fructose 6-phosphate and glyceraldehyde 3-phosphate via glycolysis

Although therapeutic strategies targeting the immune-inflammatory response (e.g., corticosteroids and immunosuppressive drugs) are effective in non-PF interstitial lung disease, they have no discernible impact on the fibrotic process in PF [31]

doi: 10.3389/fmed.2023.1124275 Received 14 December 2022 Accepted 27 February 2023 Published 22 March 2023 Volume 10 - 2023 Edited by Ana Sandoval-Rodriguez, University of Guadalajara, Mexico Reviewed by Angelo Armandi, University of Turin, Italy

Barendrecht MM et al (2007): Is the use of parasympathomimetics for treating an underactive urinary bladder evidence-based

control, 194) showed no significant effect of NAC supplementation on SHGB levels (WMD: 168 nmol/l, 95 % CI (210, 545), P = 0383) (online Supplementary Fig