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They also found that this expression change was accompanied by hypomethylation of the BLIMP1b-specific promoter

& Cardellini G

* Not recommended for pregnant or breastfeeding individuals without professional guidance

Wang et al., 2024d

A major shortcoming is their frequent failure to replicate human comorbidities (e.g., hypertension and diabetes), which profoundly alters copper homeostasis and cell death pathways

Glutathione Peroxidase 4 (GPX4) has long been considered a key protein to prevent ferroptosis, but its exact role in the progression of DKD, where this protein down-regulated, remains unclear