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16.2.2 Children with autoimmune hepatitis with cholestatic clinical or biochemical profile should be evaluated for concurrent or sequential autoimmune sclerosing cholangitis/overlap syndrome by magnetic resonance cholangiography (LOE 3, Strong recommendation)

Cheng et al., 1993

The absence of smad4 was also found to enhance mitochondrial ATP synthase inhibitory factor (ATPIF1) activity, ATP synthase inhibition, and reduce mitochondrial membrane potential, ultimately promoting glycolysis by decreasing glucose metabolic flux and increasing glucose accumulation in the podocyte [62]